I attended a conference at the Moscone Center, and came out a week ahead of time to be a tourist. Easy walk to the conference center, Trader Joes, Whole Foods, Bed, Bath & Beyond and many small coffee shops and restaurants, and to public transportation (BART, buses, cable cars, etc.). The area is slightly sketchy, but so is Market Street in some areas. I never felt uncomfortable. Highly recommend this place as an alternative to expensive hotels.