Destination guide

Heading south—a land where mountains and metropolises meld

No matter when or where you book a South America vacation rental, you'll find yourself on a remarkable continent with a vast and varied landscape. For those who love big city living, South America has plenty of thriving metropolises with world-renowned museums by day and bustling bars by night. Sandy ocean beaches, magnificent mountains, sprawling lakes, lush rainforests, and 1 of the most famous rivers in the world all beckon outdoor adventurers. Along the southern tip of the continent you'll find a drastically different landscape, complete with with towering glaciers and icebergs.


Don't forget to pack your hiking boots… and dancing shoes!

Peru's Inca Trail lets hikers take a walk in the clouds across the Andes mountain range, before ending at the abandoned Incan city of Machu Picchu. For thrilling water-based activities, take a jetboat ride near the mammoth Iguazu Falls, set along the border of Argentina and Brazil, or cool off with a swim in the Atlantic and Pacific Ocean. The Brazilian beaches of Rio de Janeiro are famous for sunbathing, soccer, and beach volleyball. If you're booking a South America vacation rental around the start of Lent, Carnaval celebrations across the continent provide all-night parties with parades, dancing, and music.


Sunscreen, scarves, snow pants, and everything in between

If you're visiting South America's tropical climates, such as the Amazon rainforest, dress for warm, humid weather as the daily temperature averages around 86 degrees and about 100 inches of rain falls each year. Some regions, like northwestern Argentina and the Atacama Desert, feature more varied climates, including warm summers, cold winters, and little rainfall. Make sure you pack a parka if you're visiting areas like Patagonia and the high Andes, where cold year-round climates include plenty of snow and temperatures well below freezing. Violent and biting winds whip through the barren landscape as well.

Natural features

Wild at heart—wandering rivers and towering waterfalls

Some of the world's most majestic waterfalls are in South America, including Venezuela's Angel Falls, 1 of the world's highest waterfalls at over 3,200 feet. The watery landscape continues as the longest river in the world, the Amazon, snakes down the continent for 4,300-plus miles. Astoundingly, more than one-third of all known species in the world live in the Amazon and its surrounding forest, including howler monkeys, sloths, dart frogs, and jaguars. The majestic peaks of the Andes mountains, which run along the western edge of South America for about 4,300 miles, play host to roaming llamas and alpacas.

Where to stay around South America?

Our 2019 property listings offer a large selection of 37,424 vacation rentals near South America. From 14,430 Houses to 383 Villas, find a unique house rental for you to enjoy a memorable stay with your family and friends. The best places to stay near South America for a holiday or a weekend are on HomeAway.

What are the most popular destinations to visit in South America?

There are many lovely places to stay for a holiday trip or just for a weekend in South America. From HomeAway travelers, the most popular destinations to visit are:

  • Cartagena: 697 vacation rentals
  • Buenos Aires: 571 vacation rentals
  • Medellin: 607 vacation rentals
  • Rio de Janeiro: 2,567 vacation rentals
  • Santiago: 339 vacation rentals

And HomeAway offers you the chance to discover many other popular destinations in South America! Please use our search bar to access the selection of vacation rentals available in other popular destinations.

What are the main cities to discover in South America?

Whether you're traveling with family or friends, here are the cities with the largest selection of vacation rentals for a holiday trip or just for a weekend in South America:

  • Cartagena: 697 rentals
  • Buenos Aires: 571 rentals
  • Medellin: 607 rentals
  • Rio de Janeiro: 2,567 rentals
  • Santiago: 339 rentals

For other cities, please use our search bar to access the selection of vacation rentals available.

Can I find easy-access vacation rentals when traveling by plane to South America?

Yes of course. Our owners offer a large selection of vacation rentals near airports. The airports with a large selection of vacation rentals in South America are:

  • Vina del Mar (KNA): 274 vacation rentals
  • Jose Maria Cordova Airport (MDE): 636 vacation rentals
  • Teniente Alejandro Velasco Astete International Airport (CUZ): 239 vacation rentals

For other airports, please use our search bar to access the selection of vacation rentals available.

Near which points of interest can I spend my holidays in South America?

HomeAway offers a large selection of rentals near lovely places in South America. From HomeAway travelers, the most popular points of interest to stay for a holiday trip or just for a weekend are:

  • Salinas Beach: 58 rentals
  • Isla Grande Beach: 114 rentals
  • Machu Picchu: 18 rentals
  • Rosario Islands Oceanarium: 21 rentals
  • Spain Square: 64 rentals

But there are many other points of interest around South America listed on HomeAway where you can find your place to stay. Just write your wanted destination in our search bar and have a look at our selection.

Explore destinations around South America

Buenos Aires
571 vacation rentals
Galápagos Islands
36 vacation rentals
Cusco Region
283 vacation rentals
Mendoza Province
80 vacation rentals
Lima Region
523 vacation rentals
Cordoba Province
61 vacation rentals
38 vacation rentals
Santiago Metropolitan Region
346 vacation rentals
661 vacation rentals
Buenos Aires Province
86 vacation rentals
62 vacation rentals
Santa Cruz
32 vacation rentals
State of São Paulo
11,173 vacation rentals
406 vacation rentals
Salta Province
41 vacation rentals
Archipelago of San Andres Providencia and Santa Catalina
83 vacation rentals
Valle del Cauca
185 vacation rentals
State of Santa Catarina
4,113 vacation rentals
State of Bahia
2,519 vacation rentals
Manabi Province
85 vacation rentals