Make a Florida vacation rental your home away from home in Florida's South Central Gulf region.

Step out the door of your Sanibel Island vacation rental and you’ll be on one of Florida's best shelling beaches. Discover the charm of Fort Myers vacation rentals, which offer easy access to dozens of golf courses and lovely beaches.

A of Sarasota vacation rental makes a great home base for enjoying the city's lively arts scene. Guests of Anna Maria Island vacation rentals can enjoy a seven-mile long beach.

You're sure to find the perfect condo rental or beachfront cottage in Florida's South Central Gulf region. Reserve your Florida vacation rental today!

Expand your search for Florida vacation rentals to include Longboat Key condos, Miami vacation rentals and Ft. Lauderdale rentals in South Florida, Destin vacation rentals and Sanibel Island rentals on the Gulf Coast, Bradenton Beach rentals, or Orlando vacation home rentals near Disney.

You have sent
a request for
information to
this owner.
Advertisement

Florida South Central Gulf Coast Rentals: Condos, Villa, Homes & More(4,502)

Sort Properties By: 
Compare Selected
1 2 3 4 5 ....151
  • Viewed

Fantastic Water Front Condo, 1st Floor, WiFi, HDTV - Mariner Pointe (951)

1 Bedrooms,
  • 1 Bathroom
    • , Sleeps 2
    1. Florida South Central Gulf Coast >
    2. Sanibel Island Condo
    22 Reviews
    #220118

    $825 - $1,425 week
    Special Offer
    ** Summer 2012 Construction Special ** (May 5 - August 31)
    • Viewed

    Wow! Updated Penthouse Beachfront Condo, Corner Unit, WiFi, HDTV, Views...

    2 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 4
    1. Florida South Central Gulf Coast >
    2. Sanibel Island Condo
    28 Reviews
    #153241

    $1,490 - $2,475 week
    • Viewed

    Luxurious Custom-Designed Contemporary Home, a Stone's Throw from the Beach

    3 Bedrooms,
  • 4 Bathrooms
    • , Sleeps 8
    1. Florida South Central Gulf Coast >
    2. North Captiva Island House
    23 Reviews
    #268650

    $1,900 - $3,700 week
    Accepts Online Payments
    • Viewed

    Ocean Views, Huge Pool, Putting Green, Luxury at Windswept!

    5 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 12
    1. Florida South Central Gulf Coast >
    2. North Captiva Island House
    48 Reviews
    #225967

    $1,927 - $5,900 week
    Accepts Online Payments
    Special Offer
    WOW! This is it! You Found Your Deal! (April 16 - June 4)
    • Viewed

    Spectacular Siesta Key Gulf Views. Quiet and Comfortable NonSmoking Condo.

    2 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Siesta Key Condo
    34 Reviews
    #173043

    $1,295 - $1,790 week
    Accepts Online Payments
    • Viewed

    Siesta Key, Siesta Beach, Twin Palms, Condo, Villa, Rental

    Studio,
  • 1 Bathroom
    • , Sleeps 2
    1. Florida South Central Gulf Coast >
    2. Siesta Key Villa
    35 Reviews
    #240948

    $85 - $130 night
    $510 - $780 week
    $1,683 - $2,574 month
    • Viewed

    Luxury 2-Bedrooms Beachfront Sundial on Gulf of Mexico

    2 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Sanibel Island Condo
    16 Reviews
    #200967

    $1,485 - $2,895 week
    • Viewed

    Beachfront on Gulf of Mexico Now Booking Summer Weeks

    1 Bedrooms,
  • 1 Bathroom
    • , Sleeps 4
    1. Florida South Central Gulf Coast >
    2. Sanibel Island Condo
    12 Reviews
    #200605

    $1,010 - $2,010 week
    • Viewed

    Siesta Key Beach Cottage Directly Across The Street From #1 Beach In The USA

    1 Bedrooms,
  • 1 Bathroom
    • , Sleeps 2
    1. Florida South Central Gulf Coast >
    2. Siesta Key Cottage
    5 Reviews
    #931257

    $800 - $1,000 week
    $2,600 - $3,400 month
    Accepts Online Payments
    • Viewed

    Tropical Breeze a Luxury Home - 60 Yards from a Fantastic Beach

    5 Bedrooms,
  • 5 Bathrooms
    • , Sleeps 10
    1. Florida South Central Gulf Coast >
    2. Captiva Island House
    54 Reviews
    #309324

    $6,665 - $6,900 week
    • Viewed

    Five Star Beachfront Condo, romantic and luxurious

    2 Bedrooms,
  • 1 Bathroom
  • , 1 Half Bath
    • , Sleeps 5
    1. Florida South Central Gulf Coast >
    2. Siesta Key Condo
    8 Reviews
    #147350

    $1,495 - $1,995 week
    $4,995 - $6,995 month
    Special Offer
    10% off the weeks of 8/25,9/1,9/15,9/22 (August 18 - September 29)
    • Viewed

    'Seawatch' on the beach at North Captiva Island

    4 Bedrooms,
  • 2 Bathrooms
  • , 1 Half Bath
    • , Sleeps 12
    1. Florida South Central Gulf Coast >
    2. North Captiva Island House
    19 Reviews
    #164483

    $1,750 - $3,200 week
    Accepts Online Payments
    • Viewed

    Siesta Key Escape

    3 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Siesta Key House
    10 Reviews
    #345147

    $1,600 - $2,000 week
    $4,500 - $5,000 month
    • Viewed

    South Facing Luxury Home and Boat on Wide Canal close to Gulf with Amazing Views

    4 Bedrooms,
  • 3 Bathrooms
    • , Sleeps 8
    1. Florida South Central Gulf Coast >
    2. Cape Coral Villa
    6 Reviews
    #940526

    $254 - $381 night
    $1,481 - $2,221 week
    $5,077 - $7,616 month
    • Viewed

    Charming and Luxury Gulf Acces Pool Home with Speedboat Close to Cape Harbour

    3 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Cape Coral Villa
    1 Reviews
    #272148

    $1,275 - $1,675 week
    $5,900 month
    • Viewed

    South Exposure Luxury Waterfront Home with Pool, Spa and a 27ft Regal boat

    3 Bedrooms,
  • 3 Bathrooms
    • , Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Cape Coral Villa
    2 Reviews
    #954821

    $158 - $237 night
    $921 - $1,381 week
    $3,157 - $4,736 month
    • Viewed

    Private Heated Pool - Near the Beach - Get away to the Island this year!

    3 Bedrooms,
  • 3 Bathrooms
    • , Sleeps 8
    1. Anna Maria Island >
    2. Holmes Beach House
    4 Reviews
    #279164

    $1,200 - $2,500 week
    • Viewed

    Waterfront Luxury Family Home, Boat (optional), Heated Pool & Jacuzzi, Fishing

    3 Bedrooms,
  • 3 Bathrooms
    • , Sleeps 8
    1. Florida South Central Gulf Coast >
    2. Cape Coral Villa
    5 Reviews
    #254128

    $999 - $1,299 week
    $3,499 - $4,199 month
    • Viewed

    Island Paradise Beach to Bay

    2 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 4
    1. Florida South Central Gulf Coast >
    2. Siesta Key Condo
    2 Reviews
    #336652

    $900 week
    • Viewed

    Overlooking the entire south end of the Island/FREE bikes & kayaks/ Great Value!

    2 Bedrooms, Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Manasota Key House
    9 Reviews
    #232898

    No rental rates available - please contact the owner
    • Viewed

    2,150 Square Foot Gulfside Beachfront Townhouse.

    2 Bedrooms,
  • 2 Bathrooms
  • , 1 Half Bath
    • , Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Siesta Key Condo
    #117853

    $1,595 week
    • Viewed

    Siesta Key Beach #1 in USA steps to Banyan Tree Beach Resort 'Key West' unit

    2 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Siesta Key House
    #218253

    $175 - $210 night
    $875 - $1,323 week
    $3,325 - $5,027 month
    • Viewed

    Beautiful Luxury Home - Private 80 Foot Floating Yacht Dock-quiet & comfortable

    4 Bedrooms,
  • 5 Bathrooms
  • , 1 Half Bath
    • , Sleeps 8
    1. Florida South Central Gulf Coast >
    2. Fort Myers House
    #911715

    $3,000 - $6,000 week
    $10,000 - $16,000 month
    • Viewed

    Island Dream-Luxury Tropical Villa with Pool and View of Skyway Bridge

    4 Bedrooms,
  • 3 Bathrooms
  • , 1 Half Bath
    • , Sleeps 10
    1. Anna Maria Island >
    2. Anna Maria House
    #911305

    No rental rates available - please contact the owner
    • Viewed

    LUXURY GULF VIEWS WITH WATERFALL POOL,STEPS TO GORGEOUS GULF BEACHES

    2 Bedrooms,
  • 1 Half Bath
    • , Sleeps 6
    1. Anna Maria Island >
    2. Holmes Beach Lodge
    2 Reviews
    #973837

    $1,280 week
    • Viewed

    Modern Newly Renovated waterfront heated pool home

    4 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 8
    1. Florida South Central Gulf Coast >
    2. Cape Coral House
    #933010

    $775 - $990 week
    $2,900 - $3,750 month
    • Viewed

    Affordable,family friendly ground floor home with a lush courtyard pool

    3 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Sanibel Island House
    #929937

    $2,700 month
    • Viewed

    True Beachfront,Lux 5 Bedroom,5 Bath, Pool & Tennis,Island's Best Private Beach

    5 Bedrooms,
  • 5 Bathrooms
    • , Sleeps 10
    1. Florida South Central Gulf Coast >
    2. North Captiva Island House
    #394262

    $3,500 week
    • Viewed

    Paradise Found, Wifi, Close to Fort Myers, Sanibel & Captiva Beache & Airport

    3 Bedrooms,
  • 2 Bathrooms
  • , 1 Half Bath
    • , Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Fort Myers Townhome
    11 Reviews
    #256016

    $700 - $800 week
    $1,400 - $1,800 month
    Accepts Online Payments
    • Viewed

    #208 Beach property, Family Friendly, Beautiful updated condo, Heated pool

    2 Bedrooms,
  • 2 Bathrooms
    • , Sleeps 6
    1. Florida South Central Gulf Coast >
    2. Longboat Key Condo
    62 Reviews
    #240486

    $163 - $189 night
    $1,140 - $1,324 week
    Accepts Online Payments
    1 2 3 4 5 ....151
    Sort Properties By: 
    Compare Selected